eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine

HOME
QUERY
- DISEASE
- GENOTYPE
NETWORK
- PHENOTYPE
- GENE
- COMMON
- DISEASE PAIR
DOWNLOAD
SUBMIT CASE
HELP&FAQ
- HELP&FAQ
- CONTACT US


	membranoproliferative glomerulonephritis

Disease ID	1311
Disease	membranoproliferative glomerulonephritis
Definition	Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
Synonym	chronic glomerulonephritis, lobular glomerulonephritides, hypocomplementemic glomerulonephritides, membranoproliferative glomerulonephritides, mesangiocapillary glomerulonephritis, hypocomplementemic glomerulonephritis, hypocomplementemic, chronic glomerulonephritis, membranoproliferative glomerulonephritis, membranoproliferative [disease/finding] glomerulonephritis, mesangiocapillary hypocomplementemic glomerulonephritides hypocomplementemic glomerulonephritis lobular glomerulonephritis mcgn mcgn - mesangiocapillary glomerulonephritis membranoproliferative glomerulonephritides membranoproliferative glomerulonephritis (mpgn) membranoproliferative glomerulonephritis nos mesangiocapillary glomerulonephritides mesangiocapillary glomerulonephritis mesangiocapillary glomerulonephritis (disorder) mesangiocapillary glomerulonephritis, nos mpgn mpgn - membranoproliferative glomerulonephritis
Orphanet	ORPHANET:54370
DOID	DOID:2920
UMLS	C0017662
MeSH	D015432
SNOMED-CT	SNOMEDCT_US_2016_09_01:80321008
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:41) C0010403 \| cryoglobulinemia \| 7 C0027726 \| nephrotic syndrome \| 6 C0017658 \| glomerulonephritis \| 5 C0035078 \| renal failure \| 4 C0022658 \| nephropathy \| 3 C0019158 \| hepatitis \| 3 C1136085 \| monoclonal gammopathy \| 3 C0010403 \| cryoglobulinaemia \| 2 C0019196 \| hepatitis c \| 2 C0038463 \| strongyloidiasis \| 2 C0796004 \| kabuki syndrome \| 1 C0017661 \| iga nephropathy \| 1 C0041227 \| trypanosomiasis \| 1 C0020676 \| hypothyroidism \| 1 C0087086 \| thrombi \| 1 C0033687 \| proteinuria \| 1 C0403416 \| crescentic glomerulonephritis \| 1 C0021053 \| immune disease \| 1 C0032463 \| polycythaemia vera \| 1 C0007102 \| colon cancer \| 1 C0011633 \| dermatomyositis \| 1 C0022658 \| renal disease \| 1 C0042769 \| virus infection \| 1 C0021400 \| influenza \| 1 C0334634 \| mantle cell lymphoma \| 1 C0022661 \| end-stage renal disease \| 1 C0024198 \| lyme disease \| 1 C0015974 \| periodic fever \| 1 C0027121 \| myositis \| 1 C0032461 \| polycythaemia \| 1 C0027697 \| nephritis \| 1 C1527336 \| sjogren's syndrome \| 1 C0920350 \| autoimmune thyroiditis \| 1 C0744421 \| immune complex glomerulonephritis \| 1 C0001126 \| renal tubular acidosis \| 1 C0019163 \| hepatitis b \| 1 C1332362 \| b-cell neoplasm \| 1 C0041228 \| african trypanosomiasis \| 1 C1389280 \| basal ganglia calcification \| 1 C0022661 \| chronic renal failure \| 1 C0019061 \| hemolytic uremic syndrome \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:5) 213 \| ALB \| CTD_human 5444 \| PON1 \| CTD_human 85480 \| TSLP \| CTD_human 712 \| C1QA \| CTD_human 3075 \| CFH \| CTD_human;UNIPROT
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:55) 58 \| ACTA1 \| 1.5 \| DISEASES 11093 \| ADAMTS13 \| 1.883 \| DISEASES 716 \| C1S \| 2.216 \| DISEASES 720 \| C4A \| 2.507 \| DISEASES 721 \| C4B \| 2.954 \| DISEASES 959 \| CD40LG \| 4.881 \| DISEASES 960 \| CD44 \| 1.46 \| DISEASES 921 \| CD5 \| 1.542 \| DISEASES 629 \| CFB \| 4.02 \| DISEASES 3075 \| CFH \| 4.983 \| DISEASES 10878 \| CFHR3 \| 3.296 \| DISEASES 10877 \| CFHR4 \| 2.357 \| DISEASES 3426 \| CFI \| 3.381 \| DISEASES 1378 \| CR1 \| 2.007 \| DISEASES 286204 \| CRB2 \| 2.147 \| DISEASES 4283 \| CXCL9 \| 1.402 \| DISEASES 29940 \| DSE \| 1.094 \| DISEASES 83715 \| ESPN \| 1.784 \| DISEASES 2335 \| FN1 \| 1.914 \| DISEASES 2526 \| FUT4 \| 1.246 \| DISEASES 2585 \| GALK2 \| 2.523 \| DISEASES 2821 \| GPI \| 1.076 \| DISEASES 3029 \| HAGH \| 2.996 \| DISEASES 26762 \| HAVCR1 \| 1.358 \| DISEASES 3106 \| HLA-B \| 1.497 \| DISEASES 3440 \| IFNA2 \| 1.858 \| DISEASES 3456 \| IFNB1 \| 1.024 \| DISEASES 3683 \| ITGAL \| 1.103 \| DISEASES 4153 \| MBL2 \| 2.449 \| DISEASES 8972 \| MGAM \| 1.293 \| DISEASES 10724 \| MGEA5 \| 1.694 \| DISEASES 4782 \| NFIC \| 1.028 \| DISEASES 25983 \| NGDN \| 1.437 \| DISEASES 51199 \| NIN \| 1.375 \| DISEASES 4868 \| NPHS1 \| 1.901 \| DISEASES 7827 \| NPHS2 \| 1.218 \| DISEASES 255743 \| NPNT \| 2.332 \| DISEASES 4925 \| NUCB2 \| 1.659 \| DISEASES 4942 \| OAT \| 1.348 \| DISEASES 340990 \| OTOG \| 3.727 \| DISEASES 23556 \| PIGN \| 2.354 \| DISEASES 2889 \| RAPGEF1 \| 3.929 \| DISEASES 6014 \| RIT2 \| 2.442 \| DISEASES 5265 \| SERPINA1 \| 1.903 \| DISEASES 5270 \| SERPINE2 \| 1.034 \| DISEASES 6614 \| SIGLEC1 \| 1.279 \| DISEASES 6575 \| SLC20A2 \| 1.286 \| DISEASES 677807 \| SNORA22 \| 3.495 \| DISEASES 7056 \| THBD \| 1.169 \| DISEASES 284486 \| THEM5 \| 1.558 \| DISEASES 8718 \| TNFRSF25 \| 1.859 \| DISEASES 7148 \| TNXB \| 1.307 \| DISEASES 51499 \| TRIAP1 \| 1.809 \| DISEASES 85480 \| TSLP \| 3.583 \| DISEASES 7272 \| TTK \| 1.303 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1311
Disease	membranoproliferative glomerulonephritis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:28) HP:0100778 \| Cryoglobulinemia \| 7 HP:0000100 \| Nephrosis \| 6 HP:0000099 \| Glomerular nephritis \| 5 HP:0000083 \| Renal insufficiency \| 4 HP:0000112 \| Nephropathy \| 3 HP:0012115 \| Liver inflammation \| 3 HP:0003774 \| End-stage renal failure \| 2 HP:0011510 \| Drusen \| 2 HP:0100820 \| Glomerulopathy \| 2 HP:0001945 \| Fever \| 1 HP:0100699 \| Scarring \| 1 HP:0002135 \| Basal ganglia calcification \| 1 HP:0012597 \| Heavy proteinuria \| 1 HP:0005575 \| Hemolytic-uremic syndrome \| 1 HP:0000821 \| Underactive thyroid \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0003003 \| Colon cancer \| 1 HP:0008653 \| Crescentic glomerulonephritis \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0000790 \| Hematuria \| 1 HP:0001947 \| Renal tubular acidosis \| 1 HP:0000093 \| Proteinuria \| 1 HP:0012592 \| Albuminuria \| 1 HP:0012574 \| Mesangial hypercellularity \| 1 HP:0000123 \| Nephritis \| 1 HP:0002049 \| Proximal renal tubular acidosis \| 1 HP:0001941 \| acidemia \| 1 HP:0005576 \| Renal interstitial fibrosis \| 1

Disease ID	1311
Disease	membranoproliferative glomerulonephritis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:16) C1963154 \| renal failure C1963084 \| colitis C1962972 \| proteinuria C1962966 \| retinopathy C1623038 \| cirrhosis C0268731 \| glomerular diseases C0264383 \| organizing pneumonia C0085679 \| hyperchloremia C0085404 \| crow-fukase syndrome C0039263 \| takayasu's arteritis C0036330 \| schistosoma mansoni infection C0027726 \| nephrotic syndrome C0022661 \| end-stage renal disease C0022661 \| chronic renal failure C0022660 \| acute renal failure C0010403 \| cryoglobulinemia
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:5) C0010403 \| cryoglobulinemia \| 7 C0027726 \| nephrotic syndrome \| 4 C0035078 \| renal failure \| 2 C0022661 \| chronic renal failure \| 1 C0022661 \| end-stage renal disease \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	1311
Disease	membranoproliferative glomerulonephritis
Case	(Waiting for update.)

Web Analytics Made Easy - StatCounter